4-溴-N,N,2,6-四甲基苯胺合成路线 （共 4 条）
反应条件
1: in water T=23°C; 2 h; Heating / reflux; 2: With sodium hydrogencarbonate in water
参考文献
Takeda Pharmaceutical Company Limited
Patent: EP1927596 A1, 2008 ;
Location in patent: Page/Page column 20-21 ;
参考文献
Westheimer; Metcalf
Journal of the American Chemical Society, 1941 , vol. 63, p. 1339,1340
反应条件
hydrogenchloride; formic acid
参考文献
Inoguchi; Achiwa
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 3 p. 818 - 820
反应条件
diethyl ether; lithium
anschliessend Behandeln mit festem Kohlendioxid;
参考文献
Westheimer; Metcalf
Journal of the American Chemical Society, 1941 , vol. 63, p. 1339,1340
