4-氰基-4'-甲基联苯合成路线 （共 60 条）
反应条件
palladium diacetate; tetrabutylammomium bromide; N-ethyl-N,N-diisopropylamine in para-xylene T=130°C; Arylation; 24 h;
参考文献
Hassan, Jwanro; Hathroubi, Chokri; Gozzi, Christel; Lemaire, Marc
Tetrahedron, 2001 , vol. 57, # 37 p. 7845 - 7855
反应条件
cis-diisothiocyanato-bis[1,3-bis(2-propenyl)benzimidazolin-2-ylidene]nickel(II) in tetrahydrofuran T=20°C; Kumada-Corriu coupling; 24 h; Inert atmosphere;
参考文献
Jothibasu, Ramasamy; Huang, Kuo-Wei; Huynh, Han Vinh
Organometallics, 2010 , vol. 29, # 17 p. 3746 - 3752
反应条件
tert.-butyl lithium; zinc(II) chloride; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; pentane Negishi reaction; 2.5 h; Heating;
参考文献
Wachall, Bertil G.; Hector, Markus; Zhuang, Yan; Hartmann, Rolf W.
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 9 p. 1913 - 1924
反应条件
palladium diacetate in ethanol T=95°C; 0.25 h; microwave irradiation;
参考文献
Kabalka, George W.; Zhou, Li-Li; Naravane, Abhijit
Tetrahedron Letters, 2006 , vol. 47, # 38 p. 6887 - 6889
反应条件
potassium acetate; palladium diacetate; N,N-dicyclohexylamine in N,N-dimethyl-formamide T=35°C; 2 h; Inert atmosphere;
参考文献
Rao, Maddali L.N.; Banerjee, Debasis; Dhanorkar, Ritesh J.
Tetrahedron Letters, 2010 , vol. 51, # 47 p. 6101 - 6104
反应条件
methyl-ethyl phosphite; Ni(acac); methyl-magnesium chloride; zinc(II) chloride in tetrahydrofuran; water T=55°C;
参考文献
Miller, Joseph A.; Farrell, Robert P.
Tetrahedron Letters, 1998 , vol. 39, # 40 p. 7275 - 7278
反应条件
caesium carbonate; palladium dichloride in N,N-dimethyl-formamide T=185°C; 20 h; Inert atmosphereSealed tube;
参考文献
Ortgies, Dirk H.; Forgione, Pat
Synlett, 2013 , vol. 24, # 13 art. no. ST-2013-S0280-L, p. 1715 - 1721
反应条件
CM-phos; H2O4P(1-)*3K(1+); palladium diacetate; triethylamine in tert-butyl alcohol T=20 - 110°C; Suzuki-Miyaura coupling; Inert atmosphere;
参考文献
Chow, Wing Kin; So, Chau Ming; Lau, Chak Po; Kwong, Fuk Yee
Journal of Organic Chemistry, 2010 , vol. 75, # 15 p. 5109 - 5112
反应条件
Ni(PCy3)2Cl2 in tetrahydrofuran; 1-methyl-pyrrolidin-2-one T=90°C; Negishi coupling reaction; 8 h; Inert atmosphere;
参考文献
Xie, Lan-Gui; Wang, Zhong-Xia
Angewandte Chemie - International Edition, 2011 , vol. 50, # 21 p. 4901 - 4904
反应条件
agarose hydrogel-supported palladium nanoparticles in methanol; water T=20°C; Suzuki-Miyaura Coupling; 10 h; Green chemistry;
参考文献
Gholinejad, Mohammad
Applied Organometallic Chemistry, 2013 , vol. 27, # 1 p. 19 - 22
