1: With hydrogenchloride; sodium nitrite in water T=0 - 5°C; 2: With hydrogenchloride; tin(ll) chloride in water T=0 - 20°C;

1.1: sodium acetate / ethanol / 20 h / Inert atmosphere; Reflux 2.1: sodium hydride / 1-methyl-pyrrolidin-2-one; mineral oil / 3.08 h / 20 - 60 °C / Inert atmosphere 2.2: 3 h / 35 °C / Inert atmosphere 3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 16 h / 20 - 50 °C / Inert atmosphere View Scheme

manganese triacetate Heating;

manganese triacetate Heating; Title compound not separated from byproducts.;

manganese triacetate Heating;

sodium hydroxide in toluene 1 h;

1: sodium hydroxide / toluene / 1 h 2: toluene-4-sulfonic acid / toluene / 16 h / Reflux; Water separator View Scheme

toluene-4-sulfonic acid in benzene 12 h; Heating;

1.1: sodium acetate / ethanol / 20 h / Inert atmosphere; Reflux 2.1: sodium hydride / 1-methyl-pyrrolidin-2-one; mineral oil / 3.08 h / 20 - 60 °C / Inert atmosphere 2.2: 3 h / 35 °C / Inert atmosphere 3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 16 h / 20 - 50 °C / Inert atmosphere 4.1: tris-(dibenzylideneacetone)dipalladium(0); sodium hydroxide / ethanol; water / 15 h / Reflux; Inert atmosphere View Scheme

manganese triacetate Heating; Title compound not separated from byproducts.;