1: 1,3-dibromo-2-iodo-benzene With tert.-butyl lithium in tetrahydrofuran; pentane T=-100°C; 4 h; 2: ortho-dibromobenzene in tetrahydrofuran; pentane T=-100 - 25°C; Product distribution / selectivity;

1: 1,3-dibromo-2-iodo-benzene With tert.-butyl lithium in tetrahydrofuran; pentane T=-100°C; 4 h; 2: ortho-dibromobenzene in tetrahydrofuran; pentane T=-100 - 25°C; 15 h; Product distribution / selectivity;

1.1: diisopropylamine; butyllithium / tetrahydrofuran; hexane / 2 h / -75 °C 1.2: 91 percent / iodine / tetrahydrofuran; hexane / -75 °C 2.1: 43 percent / butyllithium View Scheme

1.1: n-butyllithium / tetrahydrofuran; hexane / -78 °C 1.2: 0.5 h / -78 - 0 °C 1.3: 0 - 25 °C 2.1: potassium carbonate / acetone / 60 °C View Scheme

1.1: n-butyllithium / tetrahydrofuran; hexane / -78 °C 1.2: -78 - 25 °C 2.1: tert.-butyl lithium / tetrahydrofuran; pentane / 1 h / -78 °C 2.2: -78 - 25 °C View Scheme