2-氨基-5-氯烟酸甲酯合成路线

参考文献

SCHERING CORPORATION; PHARMACOPEIA DRUG DISCOVERY, INC.
Patent: WO2006/88837 A2, 2006 ;
Location in patent: Page/Page column 120 ;
WO 2006/088837 A2

14667-47-12-氨基烟酸甲酯

50735-33-62-氨基-5-氯烟酸甲酯

参考文献

Becker, Daniel P.; Flynn, Daniel L.; Moormann, Alan E.; Nosal, Roger; Villamil, Clara I.; Loeffler, Richard; Gullikson, Gary W.; Moummi, Chafiq; Yang, Dai-C.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 3 p. 1125 - 1139

5345-47-12-氨基烟酸

50735-33-62-氨基-5-氯烟酸甲酯

参考文献

Becker, Daniel P.; Flynn, Daniel L.; Moormann, Alan E.; Nosal, Roger; Villamil, Clara I.; Loeffler, Richard; Gullikson, Gary W.; Moummi, Chafiq; Yang, Dai-C.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 3 p. 1125 - 1139

107-20-0一氯乙醛+

50735-33-62-氨基-5-氯烟酸甲酯

760144-55-66-氯咪唑并[1,2-a]吡啶-8-羧酸甲酯

参考文献

Becker, Daniel P.; Flynn, Daniel L.; Moormann, Alan E.; Nosal, Roger; Villamil, Clara I.; Loeffler, Richard; Gullikson, Gary W.; Moummi, Chafiq; Yang, Dai-C.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 3 p. 1125 - 1139