4-[5-(氯甲基)-1,2,4-噁二唑-3-基]吡啶合成路线 （共 3 条）
反应条件
in xylene T=140°C; 1 h;
参考文献
Ozcan, Sevil; Kazi, Aslamuzzaman; Marsilio, Frank; Fang, Bin; Guida, Wayne C.; Koomen, John; Lawrence, Harshani R.; Sebti, Said M.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 10 p. 3783 - 3805
反应条件
1: hydroxylamine hydrochloride; sodium carbonate / water / 14 h / 70 °C 2: acetone / 0.5 h / 20 °C 3: toluene / 2 h / |Reflux; |Molecular sieve View Scheme
参考文献
Ozcan, Sevil; Kazi, Aslamuzzaman; Marsilio, Frank; Fang, Bin; Guida, Wayne C.; Koomen, John; Lawrence, Harshani R.; Sebti, Said M.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 10 p. 3783 - 3805
反应条件
1: acetone / 0.5 h / 20 °C 2: toluene / 2 h / |Reflux; |Molecular sieve View Scheme
参考文献
Ozcan, Sevil; Kazi, Aslamuzzaman; Marsilio, Frank; Fang, Bin; Guida, Wayne C.; Koomen, John; Lawrence, Harshani R.; Sebti, Said M.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 10 p. 3783 - 3805
