5-溴-3-硝基-1H-吡咯并[2,3-B]吡啶合成路线 (共 2 条)
反应条件
hydrogenchloride; SnCl2·2H2O; acetic acid T=85°C; 2 h;
参考文献
WO2013/114113 A1, ;
Page/Page column 23; 24 ;
反应条件
nitric acid
T=0°C; 0.5 h;
参考文献
VERNALIS (RandD) LIMITED; STOKES, Stephen; GRAHAM, Christoper John; RAY, Stuart Christopher; STEFANIAK, Emma Jayne
Patent: WO2013/114113 A1, 2013 ;
Location in patent: Page/Page column 23 ;