3-羧基-5-碘苯甲酸甲酯合成路线 （共 4 条）
反应条件
1: With hydrogenchloride; sodium nitrite in 1,4-dioxane; water
T=0°C; 0.25 h;
2: With potassium iodide in 1,4-dioxane; water
T=10°C; 0.166667 h;
参考文献
Iino, Tomoharu; Hashimoto, Noriaki; Sasaki, Kaori; Ohyama, Sumika; Yoshimoto, Riki; Hosaka, Hideka; Hasegawa, Takuro; Chiba, Masato; Nagata, Yasufumi; Eiki, Jun-ichi; Nishimura, Teruyuki
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 11 p. 3800 - 3809
反应条件
1: (i) SOCl2, (ii) /BRN= 1098229/
2: SnCl2, aq. HCl
3: (i) aq. NaNO2, H2SO4, (ii) aq. H2SO4
View Scheme
参考文献
Counsell,R.E. et al.
Journal of Medicinal Chemistry, 1973 , vol. 16, p. 684 - 687
反应条件
1: SnCl2, aq. HCl
2: (i) aq. NaNO2, H2SO4, (ii) aq. H2SO4
View Scheme
参考文献
Counsell,R.E. et al.
Journal of Medicinal Chemistry, 1973 , vol. 16, p. 684 - 687
反应条件
(i) aq. NaNO2, H2SO4, (ii) aq. H2SO4; Multistep reaction;
参考文献
Counsell,R.E. et al.
Journal of Medicinal Chemistry, 1973 , vol. 16, p. 684 - 687
