4-羟基 3-(苯基甲氧基)苯甲醛合成路线 （共 18 条）
参考文献
SIMES Societa Italiana Medicinali e Sintetici S.p.A.
Patent: US4673671 A1, 1987 ;
反应条件
sodium hydroxide in ethanol; water
Formylation; Reimer-Tieman formylation; Heating;
参考文献
Maekelae, Taru; Matikainen, Jorma; Waehaelae, Kristiina; Hase, Tapio
Tetrahedron, 2000 , vol. 56, # 13 p. 1873 - 1882
反应条件
hydrogenchloride in methanol; water
1 h; Reflux;
参考文献
Fumeaux, Rene; Menozzi-Smarrito, Candice; Stalmach, Angelique; Munari, Caroline; Kraehenbuehl, Karin; Steiling, Heike; Crozier, Alan; Williamson, Gary; Barron, Denis
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 22 p. 5199 - 5211
反应条件
1: 56 percent / KOH / dimethylformamide / 80 - 90 °C
2: 17 percent / NaOH / ethanol; H2O / Heating
View Scheme
参考文献
Maekelae, Taru; Matikainen, Jorma; Waehaelae, Kristiina; Hase, Tapio
Tetrahedron, 2000 , vol. 56, # 13 p. 1873 - 1882
反应条件
1: 56 percent / KOH / dimethylformamide / 80 - 90 °C
2: 17 percent / NaOH / ethanol; H2O / Heating
View Scheme
参考文献
Maekelae, Taru; Matikainen, Jorma; Waehaelae, Kristiina; Hase, Tapio
Tetrahedron, 2000 , vol. 56, # 13 p. 1873 - 1882
反应条件
potassium dichromate; sodium hydroxide
T=150°C;
参考文献
Monsanto Chem. Co.
Patent: US2168349 , 1935 ;
反应条件
copper(I) bromide in N,N-dimethyl-formamide
2.5 h; Reflux;
参考文献
Vanucci-Bacque, Corinne; Chaabouni, Slim; Fabing, Isabelle; Bedos-Belval, Florence; Baltas, Michel
Tetrahedron Letters, 2014 , vol. 55, # 2 p. 528 - 530
反应条件
sodium hydride
1.) DMF, 30 min, r.t., 2.) 24 h, 0 deg C; Yield given. Multistep reaction;
参考文献
Santangelo, Francesco; Casagrande, Cesare
Synthetic Communications, 1996 , vol. 26, # 15 p. 2863 - 2873
