甲基4-(己氧基)苯甲酸酯合成路线 （共 8 条）
反应条件
1: aq. NaOH / methanol / Heating 2: SOCl2 / Heating View Scheme
参考文献
Ili, Monica; Bucos, Madalina; Dumitracu, Florea; Circu, Viorel
Journal of Molecular Structure, 2011 , vol. 987, # 1-3 p. 1 - 6
反应条件
1: With potassium hydroxide in ethanol; water 2 h; Reflux; 2: With hydrogenchloride in ethanol; water
参考文献
New Journal of Chemistry, , vol. 37, # 10 p. 3195 - 3206
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
Percec, Virgil
Patent: US2006/88499 A1, 2006 ;
Location in patent: Page/Page column 42 ;
反应条件
1: iodine; triphenylphosphine; 1H-imidazole / dichloromethane; diethyl ether / 20 °C / |Inert atmosphere
2: (N,N'-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)CuOtBu; 1,1,3,3-tetramethyldisiloxane; cesium fluoride / 1,4-dioxane / 24 h / 0 - 25 °C / |Inert atmosphere
View Scheme
参考文献
Dang, Hester; Cox, Nick; Lalic, Gojko
Angewandte Chemie - International Edition, 2014 , vol. 53, # 3 p. 752 - 756
Angew. Chem., 2014 , vol. 126, # 3 p. 771 - 775,5
反应条件
sodium hydride
1.) THF, 0 deg C, 2.) reflux, 4 h; Multistep reaction;
参考文献
Nakai; Konno; Kosuge; Sakuyama; Toda; Arai; Obata; Katsube; Miyamoto; Okegawa; Kawasaki
Journal of Medicinal Chemistry, 1988 , vol. 31, # 1 p. 84 - 91
反应条件
hydrazine hydrate in ethanol
8 h; Heating;
参考文献
Parra, M.; Belmar, J.; Zunza, H.; Zuniga, C.; Villouta, Sh.; Martinez, R.
Journal fuer Praktische Chemie/Chemiker-Zeitung, 1995 , vol. 337, # 4 p. 325 - 327
反应条件
1: potassium hydroxide / ethanol
2: 4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide
View Scheme
参考文献
Reddy, M. Kesava; Reddy, K. Subramanyam; Narasimhaswamy; Das, Bibhuti B.; Lobo, Nitin P.; Ramanathan
New Journal of Chemistry, 2013 , vol. 37, # 10 p. 3195 - 3206
反应条件
1: aq. KOH / methanol / 12 h / Heating
2: DCC, DMAP / CH2Cl2 / 3 h / Ambient temperature
View Scheme
参考文献
Heinrich, B.; Guillon, D.
Molecular Crystals and Liquid Crystals Science and Technology, Section A: Molecular Crystals and Liquid Crystals, 1995 , vol. 268, p. 21 - 44
