2-氨基-2-甲基丙腈盐酸盐合成路线 （共 9 条）
反应条件
hydrogenchloride in diethyl ether T=0°C; 0.5 h;
参考文献
MERCK FROSST CANADA and CO.
Patent: WO2005/21487 A1, 2005 ;
Location in patent: Page/Page column 64-65 ;
反应条件
1: With ammonium chloride in water T=25°C; Strecker synthesis; 40 h; 2: With hydrogenchloride in diethyl ether T=0°C;
参考文献
Murray, Ross G.; Whitehead, David M.; Le Strat, Franck; Conway, Stuart J.
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 6 p. 988 - 991
反应条件
hydrogenchloride; ammonium chloride 1.) ammonium hydroxide, THF, 7 h (in a stoppered flask), 2.) ethyl ether; Yield given. Multistep reaction;
参考文献
Paventi, Martino; Edward, John T.
Canadian Journal of Chemistry, 1987 , vol. 65, p. 282 - 289
反应条件
potassium hydroxide; hydrogen sulfide in ammonium hydroxide; ethanol 1.) H2S was added for 1 h, 0 deg C, 2.) standing overnight (in a stoppered flask);
参考文献
Paventi, Martino; Edward, John T.
Canadian Journal of Chemistry, 1987 , vol. 65, p. 282 - 289
反应条件
sodium acetate; chlorine
参考文献
Pinchuk,A.M. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1967 , vol. 37, p. 852 - 855,802 - 804
反应条件
manganese(IV) oxide; water T=45°C; 1 h;
参考文献
Zil'berman, E. N.; Eremeev, I. V.; Abramov, A. V.
Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, p. 1243 - 1247
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 7 p. 1367 - 1371
参考文献
Biltz; Slotta
Journal fuer Praktische Chemie (Leipzig), 1926 , vol. <2>113, p. 263 Anm.4
参考文献
Wendelin, Winfried; Schramm, Hans-Wolfgang; Zmoelnig, Ilse
Monatshefte fuer Chemie, 1981 , vol. 112, p. 853 - 866
参考文献
Biltz; Slotta
Journal fuer Praktische Chemie (Leipzig), 1926 , vol. <2>113, p. 263 Anm.4
