4,6-二甲基-2,3-吡啶二胺合成路线 （共 9 条）
反应条件
hydrogen; palladium on activated charcoal in various solvent(s)
参考文献
Stucky, Gerhard C.; Roduit, Jean-Paul; Schmidt, Beat
Chimia, 1997 , vol. 51, # 6 p. 280 - 282
反应条件
ammonium hydroxide; hydrogen; palladium on activated charcoal in methanol T=50°C; P=2585.74 Torr; 18 h;
参考文献
Tanga; Bradford; Bupp; Kozocas
Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 4 p. 569 - 573
反应条件
H2; palladium monocarbide in methanol
参考文献
Merck and Co., Inc.
Patent: US5049565 A1, 1991 ;
US 5049565 A
反应条件
H2; palladium monocarbide in methanol
参考文献
Merck and Co., Inc.
Patent: US5177074 A1, 1993 ;
反应条件
1: 64 percent / potassium nitrate; concd. sulfuric acid / 1 h / 20 °C 2: 98 percent / hydrogen; ammonium hydroxide / palladium on carbon / methanol / 18 h / 50 °C / 2585.74 Torr View Scheme
参考文献
Heitsch, Holger; Becker, Reinhard H.A.; Kleemann, Heinz-Werner; Wagner, Adalbert
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 4 p. 673 - 678
反应条件
1: 59 percent / bromine; glacial acetic acid / 1.33 h / 20 °C 2: 64 percent / potassium nitrate; concd. sulfuric acid / 1 h / 20 °C 3: 98 percent / hydrogen; ammonium hydroxide / palladium on carbon / methanol / 18 h / 50 °C / 2585.74 Torr View Scheme
参考文献
Heitsch, Holger; Becker, Reinhard H.A.; Kleemann, Heinz-Werner; Wagner, Adalbert
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 4 p. 673 - 678
参考文献
Heitsch, Holger; Becker, Reinhard H.A.; Kleemann, Heinz-Werner; Wagner, Adalbert
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 4 p. 673 - 678
参考文献
Taracido, Ivan Cornella; Harrington, Edmund Martin; Hersperger, Rene; Lattmann, Rene; Miltz, Wolfgang; Weigand, Klaus
Patent: US2009/291942 A1, 2009 ;
Location in patent: Page/Page column 8-9 ;
反应条件
1: 49 percent / potassium carbonate / acetone / 18 h / 20 °C
2: lithium aluminum hydride / tetrahydrofuran / 1 h / Heating
3: 75 mg / methanol / 6 h / 120 °C
View Scheme
参考文献
Tanga; Bradford; Bupp; Kozocas
Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 4 p. 569 - 573
