反应条件
1: (1S,4R)-N-(4-chloro-2-((S)-4-cyclopropyl-1,1,1-trifluoro-2-hydroxybut 3-yn-2-yl)phenyl)-4,7,7-trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carboxamide With triethylamine in dichloromethane T=0 - 5°C; 0.333333 h; 2: 1-chloroethyl chlorocarbonate in dichloromethane T=5 - 10°C; 1 h; 3: With potassium carbonate in dichloromethane; N,N-dimethyl-formamide T=20°C;