5-(2-氟苯基)-1H-四唑合成路线 （共 6 条）
反应条件
ammonium azide; ammonium chloride; lithium chloride in N,N-dimethyl-formamide T=120 - 130°C; 24 h;
参考文献
Master, Hoshang E.; Khan, Shabana I.; Poojari, Krishna A.
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 16 p. 4891 - 4899
反应条件
1: SOCl2 / benzene / Heating 2: ammonium azide; ammonium chloride; lithium chloride / dimethylformamide / 24 h / 120 - 130 °C View Scheme
参考文献
Master, Hoshang E.; Khan, Shabana I.; Poojari, Krishna A.
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 16 p. 4891 - 4899
反应条件
1: (NH2OH)2*H2SO4; sodium acetate / ethanol / Heating 2: SOCl2 / benzene / Heating 3: ammonium azide; ammonium chloride; lithium chloride / dimethylformamide / 24 h / 120 - 130 °C View Scheme
参考文献
Master, Hoshang E.; Khan, Shabana I.; Poojari, Krishna A.
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 16 p. 4891 - 4899
反应条件
in dimethylsulfoxide-d6; chloroform-d1 Equilibrium constant;
参考文献
Butler, Richard N.; Garvin, Victor C.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 390 - 393
反应条件
in dimethylsulfoxide-d6; chloroform-d1 Equilibrium constant;
参考文献
Butler, Richard N.; Garvin, Victor C.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 390 - 393
反应条件
sodium hydroxide in ethanol; water
12 h; Heating;
参考文献
Butler, Richard N.; Garvin, Victor C.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 390 - 393
