1-BOC-4-甲氧甲基哌啶合成路线 （共 3 条）
反应条件
1: With trifluoroacetic acid in dichloromethane 2: With sodium hydroxide in dichloromethane; water
参考文献
Kelly, Nicholas Michael; Koch, Kristian Norup; Tolf, Bo-Ragnar
Patent: US2004/67931 A1, 2004 ;
Location in patent: Page/Page column 36 ;
反应条件
1: N-tert-butyloxycarbonyl-4-hydroxymethylpiperidine With sodium hydride in tetrahydrofuran
0.333333 h;
2: methyl iodide T=70°C; 4 h;
参考文献
PIRAMED LIMITED
Patent: WO2006/46031 A1, 2006 ;
Location in patent: Page/Page column 65-66 ;
WO 2006/046031 A1
反应条件
NaH in water; N,N-dimethyl-formamide; mineral oil
参考文献
Chee, Jennifer; Johanson, Jill N.; Kayser, Frank; Parsons, William H.; Rupprecht, Kathleen M.
Patent: US2002/13348 A1, 2002 ;
