4-(4-硝基苯氧基)苯甲醛合成路线 （共 11 条）
反应条件
sodium dichromate; sulfuric acid
参考文献
Suter; Oberg
Journal of the American Chemical Society, 1931 , vol. 53, p. 1566,1568
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=20°C; 3 h;
参考文献
Mishra, Amita; Batchu, Harikrishna; Srivastava, Kumkum; Singh, Pratiksha; Shukla, Pravin K.; Batra, Sanjay
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 7 p. 1719 - 1723
反应条件
CuO; potassium hydroxide in N,N-dimethyl acetamide
T=27°C; Ullmann Condensation; 24 h; Inert atmosphereSealed tube;
参考文献
Babu, S. Ganesh; Karvembu
Tetrahedron Letters, 2013 , vol. 54, # 13 p. 1677 - 1680
反应条件
1: 4-hydroxy-benzaldehyde With potassium carbonate in DMF (N,N-dimethyl-formamide)
0.166667 h;
2: 1-bromo-4-nitro-benzene in DMF (N,N-dimethyl-formamide)
3 h; Heating / reflux;
参考文献
L. MOLTENI and C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A
Patent: WO2004/35590 A2, 2004 ;
Location in patent: Page 35 ;
反应条件
caesium carbonate in N,N-dimethyl-formamide
T=90°C; 24 h;
参考文献
Arienti, Kristen L.; Brunmark, Anders; Axe, Frank U.; McClure, Kelly; Lee, Alice; Blevitt, Jon; Neff, Danielle K.; Huang, Liming; Crawford, Shelby; Pandit, Chennagiri R.; Karlsson, Lars; Breitenbucher, J. Guy
Journal of Medicinal Chemistry, 2005 , vol. 48, # 6 p. 1873 - 1885
反应条件
potassium carbonate in dimethyl sulfoxide
T=20 - 150°C; 8 h;
参考文献
Cozan, Vasile; Marin, Luminita; Bruma, Maria
Revue Roumaine de Chimie, 2005 , vol. 50, # 7-8 p. 641 - 648
反应条件
T=170°C; Erhitzen des Reaktionsgemisches auf 190-200grad;
参考文献
Suter; Oberg
Journal of the American Chemical Society, 1931 , vol. 53, p. 1566,1568
反应条件
water; nitric acid
T=15 - 25°C;
参考文献
Slotta; Soremba
Chemische Berichte, 1935 , vol. 68, p. 2059,2063
反应条件
water; nitric acid
T=15 - 25°C;
参考文献
Slotta; Soremba
Chemische Berichte, 1935 , vol. 68, p. 2059,2063
反应条件
1: HCl; AlCl3; benzene / unter Kuehlung und Behandeln des Reaktionsgemisches mit Cyanwasserstoff, erneutes Einleiten von HCl bei 40-50grad und anschliessend Erwaermen mit wss. HCl
2: water; nitric acid / 15 - 25 °C
View Scheme
参考文献
Slotta; Soremba
Chemische Berichte, 1935 , vol. 68, p. 2059,2063
