2-(3-氨基苯氧基)乙醇合成路线 （共 3 条）
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=-15 - 20°C; 2: With ammonium chloride in tetrahydrofuran
参考文献
AVILA THERAPEUTICS AND USES THEREOF
Patent: WO2009/158571 A1, 2009 ;
Location in patent: Page/Page column 252; 253 ;
WO 2009/158571 A1
反应条件
hydrazine hydrate in methanol; water T=50°C; 2.41667 h; Reflux;
参考文献
Chepyshev; Chepysheva; Ryabitskii; Prosyanik
Chemistry of Heterocyclic Compounds, 2008 , vol. 44, # 5 p. 523 - 529
Khim. Geterotsikl. Soedin.
反应条件
1: aqueous NaOH / auf Siedetemperatur 2: Hydrogenation View Scheme
参考文献
AGIOS PHARMACEUTICALS, INC.; LEMIEUX, Rene M.; POPOVICI-MULLER, Janeta; TRAVINS, Jeremy; CAI, Zhenwei; CUI, Dawei; ZHOU, Ding
Patent: WO2013/107291 A1, 2013 ;
