5-氨基-1H-咪唑-4-甲腈合成路线 （共 22 条）
反应条件
1: With methanesulfonic acid in tetrahydrofuran T=40°C; 1 h; 2: With ammonia in tetrahydrofuran; water T=30°C; 1 h;
参考文献
EP2138480 A1, ;
Page/Page column 15-16 ;
反应条件
1: With sodium hydroxide in water T=30 - 40°C; 1 h; 2: With hydrogenchloride in water pH=6;
参考文献
EP2138480 A1, ;
Page/Page column 15 ;
反应条件
sodium hydroxide in water T=20°C; 20 h;
参考文献
EP2138480 A1, ;
Page/Page column 16 ;
反应条件
trichlorophosphate 3.5 h; Heating / reflux;
参考文献
EP1420021 A1, ;
Page 24 ;
反应条件
ammonia in methanol 0.0833333 h;
参考文献
Journal of Organic Chemistry, , vol. 53, # 2 p. 382 - 386
反应条件
in chloroform T=5°C; 2 h;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 25, # 9 p. 1045 - 1047
Khimiya Geterotsiklicheskikh Soedinenii, , # 9 p. 1248 - 1250
反应条件
1-methylguanidine hydrochloride; 1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran; ethanol T=10°C; 1728 h; Inert atmosphere;
参考文献
Arkivoc, , vol. 2010, # 5 p. 82 - 91
反应条件
ammonium hydroxide T=120 - 130°C; 2 h; high pressure;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 19, # 11 p. 1231 - 1234
Khimiya Geterotsiklicheskikh Soedinenii, , # 11 p. 1548 - 1551
反应条件
ammonium hydroxide in ethanol 1 h; Ambient temperature;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 19, # 11 p. 1231 - 1234
Khimiya Geterotsiklicheskikh Soedinenii, , # 11 p. 1548 - 1551
反应条件
in water Ambient temperaturebase;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 6 p. 1705 - 1712
