5-氨基-1H-咪唑-4-甲腈合成路线 （共 22 条）
反应条件
1: With N,O-bis-(trimethylsilyl)-acetamide; trimethylsilyl trifluoromethanesulfonate in acetonitrile T=130°C; Vorbrueggen glycosylation; 0.0833333 h; microwave irradiation; 2: With ammonia in methanol T=50°C; 16 h; Title compound not separated from byproducts;
参考文献
Bookser, Brett C.; Raffaele, Nicholas B.
Journal of Organic Chemistry, 2007 , vol. 72, # 1 p. 173 - 179
反应条件
1: With N,O-bis-(trimethylsilyl)-acetamide; trimethylsilyl trifluoromethanesulfonate in acetonitrile T=130°C; Vorbrueggen glycosylation; 0.0833333 h; microwave irradiation; 2: With ammonia in methanol T=50°C; 16 h; Title compound not separated from byproducts;
参考文献
Bookser, Brett C.; Raffaele, Nicholas B.
Journal of Organic Chemistry, 2007 , vol. 72, # 1 p. 173 - 179
反应条件
potassium carbonate in tetrahydrofuran; N,N-dimethyl-formamide
48 h; Ambient temperature;
参考文献
Grozinger; Freter; Farina; Gladczuk
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 3 p. 221 - 226
反应条件
potassium carbonate in tetrahydrofuran; N,N-dimethyl-formamide
48 h; Ambient temperature;
参考文献
Grozinger; Onan
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 3 p. 737 - 745
反应条件
potassium carbonate in tetrahydrofuran; N,N-dimethyl-formamide
48 h; Ambient temperature;
参考文献
Grozinger; Freter; Farina; Gladczuk
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 3 p. 221 - 226
反应条件
potassium carbonate in tetrahydrofuran; N,N-dimethyl-formamide
18 h; Heating;
参考文献
Grozinger; Onan
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 3 p. 737 - 745
反应条件
potassium carbonate in tetrahydrofuran; N,N-dimethyl-formamide
48 h; Ambient temperature; Title compound not separated from byproducts;
参考文献
Grozinger; Freter; Farina; Gladczuk
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 3 p. 221 - 226
反应条件
potassium carbonate in tetrahydrofuran; N,N-dimethyl-formamide
48 h; Ambient temperature;
参考文献
Grozinger; Freter; Farina; Gladczuk
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 3 p. 221 - 226
反应条件
potassium carbonate in tetrahydrofuran; N,N-dimethyl-formamide
7 h; Heating;
参考文献
Grozinger; Onan
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 3 p. 737 - 745
反应条件
potassium carbonate in tetrahydrofuran; N,N-dimethyl-formamide
48 h; Ambient temperature;
参考文献
Grozinger; Freter; Farina; Gladczuk
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 3 p. 221 - 226
