5-氯-1,2,3-噻二唑-3-胺合成路线 (共 2 条)
反应条件
1: in dichloromethane
T=-10°C;
2: With sodium hydroxide in dichloromethane; water
T=-20 - 20°C;
参考文献
KALYPSYS, INC.
Patent: WO2007/76460 A2, 2007 ;
Location in patent: Page/Page column 23; 24 ;
WO 2007/076460 A2
反应条件
1: ethane-1,2-dial; 3-amino-5-chloro-1,2,4-thiadiazole in ethanol
T=80°C; 4 h;
2: formaldehyd With phosphoric acid; ammonium chloride in ethanol
参考文献
KALYPSYS, INC.
Patent: WO2007/76460 A2, 2007 ;
Location in patent: Page/Page column 23; 24; 25 ;
WO 2007/076460 A2