1-甲基-2-吗啉-4-乙胺合成路线 (共 3 条)
反应条件
1: With methylamine in ethanol T=40°C; 4 h; 2: With sodium cyanoborohydride in dichloromethane T=20°C; 2 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2005/60970 A1, 2005 ;
Location in patent: Page/Page column 135 ;
WO 2005/060970 A1
参考文献
Chechik, V. O.; Bobylev, V. A.
Russian Journal of General Chemistry, 1994 , vol. 64, # 10.2 p. 1501 - 1502
Zhurnal Obshchei Khimii, 1994 , vol. 64, # 10 p. 1685 - 1687
反应条件
(i), (ii) aq. HCl; Multistep reaction;
参考文献
Savignac,P. et al.
Journal of Organometallic Chemistry, 1973 , vol. 60, p. 103 - 113