19-羟基-4-雄甾烯-3,17-二酮合成路线 （共 36 条）
反应条件
336 h; Rhodotorula mucilaginosa;
参考文献
Dmochowska-Gladysz, Jadwiga; Tlomak, Elzbieta; Siewinski, Antoni
Bulletin de l'Academie Polonaise des Sciences, Serie des Sciences Chimiques, 1980 , vol. 28, # 1 p. 1 - 8
反应条件
D-glucose T=29 - 30°C; 168 h; Moraxella sp.;
参考文献
Shankar, V. N.; Row, T. N. Guru; Madyastha, K. M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 18 p. 2233 - 2236
反应条件
mit Hilfe eines Homogenats aus Rinder-Nebennieren;
参考文献
Meyer
Experientia, 1955 , vol. 11, p. 99
反应条件
mit Hilfe eines Homogenats aus Rinder-Nebennieren;
参考文献
Meyer
Experientia, 1955 , vol. 11, p. 99
反应条件
Yield given. Multistep reaction;
参考文献
Holland; Taylor
Canadian Journal of Chemistry, 1981 , vol. 59, # 19 p. 2809 - 2819
反应条件
1: 60 percent / pyridinium dichromate / CH2Cl2 / 18 h / 20 °C 2: 3.3 percent / Zn, 50percent aq. AcOH / 1.5 h View Scheme
参考文献
Templeton, John F.; Ling, Yangzhi; Lin, Weiyang; Pitura, Randy J.; Marat, Kirk; Bridson, John N.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 9 p. 1149 - 1158
反应条件
1: 7.3 g / Cr2O3, conc. H2SO4 / acetone / 0.5 h / 10 - 15 °C 2: 700 mg / pyridine / 1 h / 50 °C 3: 5.1 g / malonic acid / 19 h View Scheme
参考文献
Templeton, John F.; Ling, Yangzhi; Lin, Weiyang; Pitura, Randy J.; Marat, Kirk; Bridson, John N.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 9 p. 1149 - 1158
反应条件
alpha,alpha-dimethylbenzyl hydroperoxide; 1-methyl-1H-imidazole; [5,10,15,20-tetrakis(2,6-dichlorophenyl)porphinato]iron(III) chloride in dichloromethane T=12°C; 25 h;
参考文献
Tetrahedron Letters, , vol. 31, # 43 p. 6223 - 6226
反应条件
2: 96 percent / N-bromosuccinimide, 2,2'-azobisisobutyronitrile / CCl4 / 1.5 h / Heating 3: 8.5 percent / potassium acetate / acetic acid / 0.25 h / Heating 4: 96 percent / aq. 48percent HF / acetonitrile / 1.5 h / Ambient temperature 5: 70 percent / pyridinium chlorochromate / CH2Cl2 / 2.5 h 6: KHCO3 / methanol; H2O / Ambient temperature; further reagents View Scheme
参考文献
Templeton, John F.; Lin, Weiyang; Ling, Yangzhi; Majgier-Baranowska, Helena; Marat, Kirk
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 14 p. 2037 - 2043
反应条件
phenazine methosulfate T=30°C; 1 h; sterois 1,2-dehydrogenase, phosphate buffer (pH 7.5); transformation of 3β-acetoxycholest-5-en-19-ol and 19-hydroxyandrost-4-ene-3,17-dione by Moraxella sp.; Product distribution;
参考文献
Shankar, V. N.; Row, T. N. Guru; Madyastha, K. M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 18 p. 2233 - 2236
