N-苄氧羰基-4-氨基丁酸合成路线 （共 42 条）
反应条件
phosphate buffer; Bacillus subtilis esterase BS2 in methanol; hexane T=37°C; pH=7.4; 1.5 h; Product distribution; Further Variations:reaction times;
参考文献
Fotakopoulou, Irene; Barbayianni, Efrosini; Constantinou-Kokotou, Violetta; Bornscheuer, Uwe T.; Kokotos, George
Journal of Organic Chemistry, 2007 , vol. 72, # 3 p. 782 - 786
反应条件
phosphate buffer; Bacillus subtilis esterase BS2 in methanol; hexane T=37°C; pH=7.4; 0.25 h; Product distribution; Further Variations:reaction times; enzyme/substrate ratios;
参考文献
Fotakopoulou, Irene; Barbayianni, Efrosini; Constantinou-Kokotou, Violetta; Bornscheuer, Uwe T.; Kokotos, George
Journal of Organic Chemistry, 2007 , vol. 72, # 3 p. 782 - 786
反应条件
hydrogenchloride; bis(1,5-cyclooctadiene)nickel (0); 2,9-dimethyl-1,10-phenanthroline 1.) THF, reflux, 2.5h.; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Castano; Echavarren
Tetrahedron Letters, 1990 , vol. 31, # 33 p. 4783 - 4786
反应条件
in water; acetonitrile 0.25 h; Irradiation;
参考文献
Arumugam, Selvanathan; Popik, Vladimir V.
Photochemical and Photobiological Sciences, 2012 , vol. 11, # 3 p. 518 - 521
反应条件
(i) tBu3SnN3, dioxane, (ii) /BRN= 878307/, (iii) aq. NaOH; Multistep reaction;
参考文献
Kricheldorf,H.R. et al.
Angewandte Chemie, 1977 , vol. 89, p. 570 - 572
反应条件
in methanol 1.4 h; UV-irradiationaq. HEPES buffer; Kinetics; WavelengthTime;
参考文献
Soares, Ana M. S.; Costa, Susana P. G.; Goncalves, M. Sameiro T.
Amino Acids, 2010 , vol. 39, # 1 p. 121 - 133
反应条件
in methanol 0.65 h; UV-irradiationaq. HEPES buffer; Kinetics; WavelengthTime;
参考文献
Soares, Ana M. S.; Costa, Susana P. G.; Goncalves, M. Sameiro T.
Amino Acids, 2010 , vol. 39, # 1 p. 121 - 133
反应条件
oxalyl dichloride in dichloromethane T=20°C; 4 h;
参考文献
Guenin, Erwann; Monteil, Maelle; Bouchemal, Nadia; Prange, Thierry; Lecouvey, Marc
European Journal of Organic Chemistry, 2007 , # 20 p. 3380 - 3391
反应条件
4-(N,N-dimethlyamino)pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride
参考文献
Gibbs, Gary; Hateley, Martin J.; McLaren, Lee; Welham, Matthew; Willis, Christine L.
Tetrahedron Letters, 1999 , vol. 40, # 5 p. 1069 - 1072
反应条件
polymer-supported diphenylphosphoryl azide; triethylamine 24 h; Heating;
参考文献
Lu, Yuhua; Taylor, Richard T.
Heterocycles, 2004 , vol. 62, p. 869 - 876
