2-羟基-1-(4-吗啉)乙酮合成路线 （共 5 条）
反应条件
hydrogen; Cu/Al2O3/SiO2 in methanol
T=170°C; P=41254.1 Torr; 16.5 h; Autoclave;
参考文献
SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.; DE BOER, Eric Johannes Maria; VAN DER HEIJDEN, Harry; MEURS, Jan Hermen Hendrik; WIJNANS, Sanne
Patent: WO2010/130696 A1, 2010 ;
Location in patent: Page/Page column 10-12 ;
反应条件
in toluene
14 h; Heating;
参考文献
Boyko, Vyacheslav I.; Rodik, Roman V.; Severenchuk, Inna N.; Voitenko, Zoya V.; Kalchenko, Vitaly I.
Synthesis, 2007 , # 14 p. 2095 - 2096
参考文献
Baindur, Nand; Gaul, Michael David; Kreutter, Kevin Douglas; Baumann, Christian Andrew; Kim, Alexander J.; Xu, Guozhang; Tuman, Robert W.; Johnson, Dana L.
Patent: US2006/281772 A1, 2006 ;
Location in patent: Page/Page column 120 ;
US 20060281772 A1
反应条件
potassium chloride in phosphate buffer; acetonitrile
T=37°C; pH=7.4; 0.266667 h; Enzymatic reaction; Kinetics;
参考文献
Talath, Sirajunisa; Shirote, Pramod J.; Lough, W. John; Gadad, Andanappa K.
Arzneimittel-Forschung/Drug Research, 2006 , vol. 56, # 9 p. 631 - 639
反应条件
sodium hydride in tetrahydrofuran
0.2 h; Heating;
参考文献
Schank, Kurt; Bouillon, Guenter; Fuenfrocken, Michael; Lick, Carlo; Lieder, Robert
Helvetica Chimica Acta, 2002 , vol. 85, # 5 p. 1295 - 1326
