1-(甲苯-4-磺酰基)-吡咯烷-2-羧酸合成路线 （共 8 条）
反应条件
hydrogen bromide; acetic acid
参考文献
Pravda; Rudinger
Collection of Czechoslovak Chemical Communications, 1955 , vol. 20, p. 1,7
反应条件
sodium carbonate
Inert atmosphere;
参考文献
Hugenberg, Verena; Froehlich, Roland; Haufe, Guenter
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 24 p. 5682 - 5691
反应条件
N,N,N',N,-tetramethylethylenediamine; zinc in N,N-dimethyl-formamide
T=0°C; Reduction; esterification; 4.5 h;
参考文献
Katz, Thomas J.; Liu, Longbin; Willmore, Nikolaos D.; Fox, Joseph M.; Rheingold, Arnold L.; Shi, Shuhao; Nuckolls, Colin; Rickman, Barry H.
Journal of the American Chemical Society, 1997 , vol. 119, # 42 p. 10054 - 10063
参考文献
McChesney; Swann
Journal of the American Chemical Society, 1937 , vol. 59, p. 1116
反应条件
1: Et3N / tetrahydrofuran / 20 °C
2: 74 percent / CH2Cl2 / 24 h / -78 °C
3: aq. NaOH / tetrahydrofuran / 0.5 h / 20 °C
View Scheme
参考文献
Itoh, Takashi; Matsuya, Yuji; Enomoto, Yasuko; Ohsawa, Akio
Tetrahedron, 2001 , vol. 57, # 34 p. 7277 - 7289
反应条件
1: 74 percent / CH2Cl2 / 24 h / -78 °C
2: aq. NaOH / tetrahydrofuran / 0.5 h / 20 °C
View Scheme
参考文献
Itoh, Takashi; Matsuya, Yuji; Enomoto, Yasuko; Ohsawa, Akio
Tetrahedron, 2001 , vol. 57, # 34 p. 7277 - 7289
参考文献
Evans,D.A.; Nelson,J.V.; Vogel,E.
Journal of the American Chemical Society, 1981 , vol. 103, p. 3099
反应条件
sodium hydrogencarbonate; acetone
参考文献
Pravda; Rudinger
Collection of Czechoslovak Chemical Communications, 1955 , vol. 20, p. 1,7
