2-氨基-3-氯苯乙酮盐酸盐合成路线 （共 5 条）
反应条件
hydrogenchloride in ethanol; water
T=0 - 50°C; 3 h;
参考文献
Shinonogi and Co., Ltd
Patent: US2011/28468 A1, 2011 ;
Location in patent: Page/Page column 27 ;
参考文献
Maeda; Suzuki; Iwasaki; Matsumoto; Iwasawa
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 7 p. 2536 - 2543
反应条件
1: chloroform / 2 h / 0 - 50 °C
2: hydrogenchloride / ethanol; water / 3 h / 0 - 50 °C
View Scheme
参考文献
ShionogiandCo., Ltd.
Patent: EP2280000 A1, 2011 ;
反应条件
1: tetrabutylammomium bromide / acetonitrile / 0.03 h / 150 °C / Microwave irradiation; Sealed tube
2: chloroform / 2 h / 0 - 50 °C
3: hydrogenchloride / ethanol; water / 3 h / 0 - 50 °C
View Scheme
参考文献
ShionogiandCo., Ltd.
Patent: EP2280000 A1, 2011 ;
反应条件
hydrogenchloride; diethyl ether; tin(ll) chloride
参考文献
Edkins; Linnell
Quarterly Journal of Pharmacy and Pharmacology, 1936 , vol. 9, p. 75,102
