5,10,15,20-四(4-氨基苯)-21H,23H-卟啉合成路线 （共 14 条）
反应条件
1: 5,10,15,20-tetrakis(4-hydroxyphenyl)-porphyrin With nickel diacetate in N,N-dimethyl-formamide T=80°C; Metallation; 2 h; 2: chloroacetic acid With sodium hydroxide in water T=90°C; Substitution; 2 h; 3: With trifluoroacetic acid in chloroform T=20°C; Hydrogenation; 3 h;
参考文献
He, Yu-Feng; Wei, Dong-Bin; Chen, Hui
Synthetic Communications, 1998 , vol. 28, # 15 p. 2843 - 2849
反应条件
1: 35 percent / K2CO3, KI / dimethylformamide / 2 h / Heating 2: 82 percent / 10percent KOH, water / ethanol / 1 h / Heating View Scheme
参考文献
Syrbu, S. A.; Semeikin, A. S.; Berezin, B. D.; Koifman, O. I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1989 , vol. 25, # 10 p. 1149 - 1153
Khimiya Geterotsiklicheskikh Soedinenii, 1989 , vol. 25, # 10 p. 1373 - 1377
反应条件
potassium carbonate in N,N-dimethyl-formamide 2 h; Heating; Yield given;
参考文献
Semeikin, A. S.; Koifman, O. I.; Nikitina, G. E.; Berezin, B. D.
J. Gen. Chem. USSR (Engl. Transl.), 1984 , vol. 54, # 7 p. 1599 - 1603,1423 - 1426
反应条件
potassium carbonate in N,N-dimethyl-formamide
Etherification; 2 h; Heating;
参考文献
Syrbu; Semeikin
Russian Journal of Organic Chemistry, 1999 , vol. 35, # 8 p. 1236 - 1239
