DL-5-苯甲酰氨基-5-苄基-4-氧代-1,3-二氧烷合成路线 （共 5 条）
反应条件
1.1: aq. NaOH / dioxane / 1 h / 20 °C 1.2: cinchonidine / ethanol / 6 h 1.3: 73.8 percent / aq. HCl / 0.5 h 2.1: 86.2 percent / pyridine / 72 h / 5 °C 3.1: 74.9 percent / NaI; Zn / dimethylformamide / 10 h / 120 °C 4.1: 82.1 percent / HCl / 10 h / Heating View Scheme
参考文献
Olma
Polish Journal of Chemistry, 1996 , vol. 70, # 11 p. 1442 - 1447
反应条件
1.1: aq. NaOH / dioxane / 1 h / 20 °C 1.2: cinchonidine / ethanol / 6 h 1.3: aq. HCl / 0.5 h 2.1: 90 percent / pyridine / 72 h / 5 °C 3.1: 72.4 percent / NaI; Zn / dimethylformamide / 10 h / 120 °C 4.1: 80.3 percent / HCl / 10 h / Heating View Scheme
参考文献
Shiraiwa, Tadashi; Suzuki, Masahiro; Sakai, Yoshio; Nagasawa, Hisashi; Takatani, Kazuhiro; Noshi, Daisuke; Yamanashi, Kenji
Chemical and pharmaceutical bulletin, 2002 , vol. 50, # 10 p. 1362 - 1366
反应条件
pyridine in water
T=20°C; 12 h;
参考文献
Shiraiwa, Tadashi; Suzuki, Masahiro; Sakai, Yoshio; Nagasawa, Hisashi; Takatani, Kazuhiro; Noshi, Daisuke; Yamanashi, Kenji
Chemical and pharmaceutical bulletin, 2002 , vol. 50, # 10 p. 1362 - 1366
反应条件
1: Ac2O / 1 h / 95 °C
2: 121 g / pyridine / H2O / 12 h / 20 °C
View Scheme
参考文献
Shiraiwa, Tadashi; Suzuki, Masahiro; Sakai, Yoshio; Nagasawa, Hisashi; Takatani, Kazuhiro; Noshi, Daisuke; Yamanashi, Kenji
Chemical and pharmaceutical bulletin, 2002 , vol. 50, # 10 p. 1362 - 1366
反应条件
sodium hydroxide in 1,4-dioxane
1 h;
参考文献
Olma
Polish Journal of Chemistry, 1996 , vol. 70, # 11 p. 1442 - 1447
