反应条件
1: 1.) H2, 1M NaOH / 1.) 10percent Pd/C / 1.) EtOH, 1.5 h, 2.) EtOH, -60 deg C, 5 h 2: 90 percent / ICl / CH2Cl2 / 0.5 h / Ambient temperature 3: 75 percent / RuCl3*H2O, NaIO4 / CCl4; acetonitrile; H2O / 1.25 h / Ambient temperature 4: 1.) ZnCl2, 2.) dichlorobis(triphenylphosphine)palladium(II), DIBALH / 1.) ether, THF, RT, 10 min, 2.) ether, THF, RT, 1.5 h View Scheme
参考文献
Hamon, David P.G.; Massy-Westropp, Ralph A.; Newton, Josephine L.
Tetrahedron, 1995 , vol. 51, # 46 p. 12645 - 12660