5-羟基-2-癸烯酸-δ-内酯合成路线 （共 63 条）
反应条件
2,2,6,6-tetramethyl-piperidine-N-oxyl; [bis(acetoxy)iodo]benzene in dichloromethane T=20°C; 24 h; Inert atmosphere;
参考文献
Bartlett, Sean; Boese, Dietrich; Ghori, Daniel; Mechsner, Bastian; Pietruszka, Joerg
Synthesis (Germany), 2013 , vol. 45, # 8 art. no. SS-2013-T0089-OP, p. 1106 - 1114
反应条件
RuCl2(tricyclohexylphosphine)2(benzylidene); titanium(IV) isopropylate in dichloromethane RefluxInert atmosphere;
参考文献
Harbindu, Anand; Kumar, Pradeep
Synthesis, 2011 , # 12 art. no. C28811SS, p. 1954 - 1959
反应条件
quinoline; hydrogen; palladium on barium sulfate in tetrahydrofuran
参考文献
Midland, M. Mark; Tramontano, Alfonso; Kazubski, Aleksander; Graham, Richard S.; Tsai, David J. S.; Cardin, Daniel B.
Tetrahedron, 1984 , vol. 40, # 8 p. 1371 - 1380
反应条件
1: With oxygen; ozone in methanol T=-78°C; 2: With sodium tetrahydroborate in methanol T=-78 - 20°C; 3: With toluene-4-sulfonic acid; methanesulfonyl chloride; triethylamine in dichloromethane T=20°C; 14 h;
参考文献
Mineeva
Russian Journal of Organic Chemistry, 2013 , vol. 49, # 7 p. 979 - 985
Zh. Org. Khim., 2013 , vol. 49, # 7 p. 995 - 1001,7
反应条件
pyridine; trichlorophosphate T=65°C; 5 h;
参考文献
Bennett, Frank; Knight, David W.; Fenton, Garry
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 6 p. 1543 - 1547
反应条件
1: copper(I) iodide / tetrahydrofuran / -50 - 0 °C 2: sodium acetate; peracetic acid / toluene / 6 h / 45 °C 3: acetic acid / ethanol; H2O / 4 h / 60 °C 4: HCl / Heating View Scheme
参考文献
Haase, Bernhard; Schneider, Manfred P.
Tetrahedron: Asymmetry, 1993 , vol. 4, # 5 p. 1017 - 1026
反应条件
water; toluene-4-sulfonic acid in toluene 1.5 h; Heating;
参考文献
Haase, Bernhard; Schneider, Manfred P.
Tetrahedron: Asymmetry, 1993 , vol. 4, # 5 p. 1017 - 1026
反应条件
1: With toluene-4-sulfonic acid in methanol T=20°C; 0.5 h; 2: in benzene T=20°C; 1 h; Further stages.;
参考文献
Sabitha, Gowravaram; Gopal; Yadav
Synthetic Communications, 2007 , vol. 37, # 9 p. 1495 - 1502
反应条件
1: With ethylaluminum dichloride in diethyl ether; hexane T=-45 - -30°C; 2 h; 2: With hydrogen fluoride in acetonitrile T=50°C; 4 h; Further stages.;
参考文献
Fournier, Lycia; Kocienski, Philip; Pons, Jean-Marc
Tetrahedron, 2004 , vol. 60, # 7 p. 1659 - 1663
反应条件
1: 82 percent / triethylamine / CH2Cl2 / 0 - 20 °C 2: 78 percent / bis(tricyclohexylphosphine) benzylidene Ru(IV) dichloride / CH2Cl2 / 6 h / Heating View Scheme
参考文献
Gupta, Priti; Naidu, S. Vasudeva; Kumar, Pradeep
Tetrahedron Letters, 2004 , vol. 45, # 4 p. 849 - 851
