MP-carbonate in tetrahydrofuran 49 h; Heating / reflux;

1: thiobenzoic acid S-(4,4,5,5,5-pentafluoro-pentyl)ester With potassium tert-butylate in methanol 0.5 h; 2: 9-bromononan-1-ol

sodium hydroxide in water; acetonitrile T=40 - 72°C; 83 h; Inert atmosphereLarge scale reaction;

1: isopropyl alcohol; toluene / 20 h / Reflux; Large scale reaction 2: sodium hydroxide / water; acetonitrile / 83 h / 40 - 72 °C / Inert atmosphere; Large scale reaction View Scheme

1: hydrogen bromide / water; toluene / 7 h / Reflux; Large scale reaction 2: isopropyl alcohol; toluene / 20 h / Reflux; Large scale reaction 3: sodium hydroxide / water; acetonitrile / 83 h / 40 - 72 °C / Inert atmosphere; Large scale reaction View Scheme

1: triethylamine / acetonitrile / 2 h / 20 °C / Inert atmosphere; Large scale reaction 2: sodium hydroxide / water; acetonitrile / 83 h / 40 - 72 °C / Inert atmosphere; Large scale reaction View Scheme

bromine; triphenylphosphine in acetonitrile T=23°C; 3 h; Large scale reaction;