2-甲基-1-吗啉-2-丙烯-1-酮合成路线 (共 2 条)
反应条件
pyridine in dichloromethane
T=0 - 23°C; 1 h; Inert atmosphere;
参考文献
Allais, Christophe; Tsai, Andy S.; Nuhant, Philippe; Roush, William R.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 49 p. 12888 - 12891
Angew. Chem., 2013 , vol. 125, # 49 p. 13126 - 13129,4
反应条件
1: 3,4-dihydro-2H-pyran With tert.-butyl lithium in tetrahydrofuran; pentane
T=-78 - -5°C; 1 h;
2: 4-methacryloylmorpholine in tetrahydrofuran; pentane
T=-78°C; 1 h;
参考文献
Bee, Cisco; Leclerc, Eric; Tius, Marcus A.
Organic Letters, 2003 , vol. 5, # 26 p. 4927 - 4930