2-(4-苯氧基苯基)-乙胺合成路线 （共 16 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=20°C; 3 h;
参考文献
AKAAL PHARMA PTY LTD; GILL, Gurmit, S.; GROBELNY, Damian, W.
Patent: WO2010/42998 A1, 2010 ;
Location in patent: Page/Page column 98 ;
WO 2010/042998 A1
反应条件
1: With trifluoroacetic acid in dichloromethane 16 h; 2: With sodium hydroxide in dichloromethane
参考文献
Rigel Pharmaceuticals, Inc.; Goff, Dane; Payan, Donald G.; Braselmann, Sylvia
Patent: US2013/237524 A1, 2013 ;
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
参考文献
Japan Tobacco Inc.
Patent: US6017919 A1, 2000 ;
反应条件
sodium hydroxide in diethyl ether; water
参考文献
Rigel Pharmaceuticals, Inc.; Goff, Dane; Payan, Donald G.; Braselmann, Sylvia
Patent: US2013/237524 A1, 2013 ;
Location in patent: Paragraph 0226 ;
反应条件
1: ammonium acetate; nitromethane; acetic acid / 3 h / 20 °C / sonication 2: LiAlH4 / tetrahydrofuran / 6 h / 65 °C View Scheme
参考文献
Yamu, Xia; Yinglan, Guo; Yanling, Wen
Journal of the Serbian Chemical Society, 2010 , vol. 75, # 12 p. 1617 - 1623
反应条件
1: potassium carbonate / acetone / 15 h / Reflux 2: trifluoroacetic acid / dichloromethane / 16 h View Scheme
参考文献
Yamu, Xia; Yinglan, Guo; Yanling, Wen
Journal of the Serbian Chemical Society, 2010 , vol. 75, # 12 p. 1617 - 1623
反应条件
1: potassium carbonate / acetone / 15 h / Reflux 2: trifluoroacetic acid / dichloromethane / 16 h View Scheme
参考文献
Rigel Pharmaceuticals, Inc.; Goff, Dane; Payan, Donald G.; Braselmann, Sylvia
Patent: US2013/237524 A1, 2013 ;
反应条件
1: SOCl2, Py 2: dimethylsulfoxide 3: LiAlH4 View Scheme
参考文献
Barton,D.H.R. et al.
Journal of the Chemical Society, 1963 , p. 4545 - 4558
反应条件
1: dimethylsulfoxide 2: LiAlH4 View Scheme
参考文献
Barton,D.H.R. et al.
Journal of the Chemical Society, 1963 , p. 4545 - 4558
反应条件
1: potassium carbonate / acetone / 20 °C 2: sodium hydroxide / methanol; water / 5 h / Cooling with ice 3: lithium aluminium tetrahydride / diethyl ether / 4 h / Reflux; Inert atmosphere View Scheme
参考文献
Yamu, Xia; Yinglan, Guo; Yanling, Wen
Journal of the Serbian Chemical Society, 2010 , vol. 75, # 12 p. 1617 - 1623
