(S)-(+)-1-(2-吡咯烷甲基)吡咯烷合成路线 （共 15 条）
反应条件
1: 91 percent / PTSA / toluene / 16 h / Heating 2: 95 percent / acetonitrile / 0.17 h / 20 °C 3: 90 percent / LiAlH4 / tetrahydrofuran / Heating View Scheme
参考文献
Amedjkouh, Mohamed; Ahlberg, Per
Tetrahedron Asymmetry, 2002 , vol. 13, # 20 p. 2229 - 2234
反应条件
1: 95 percent / acetonitrile / 0.17 h / 20 °C 2: 90 percent / LiAlH4 / tetrahydrofuran / Heating View Scheme
参考文献
Amedjkouh, Mohamed; Ahlberg, Per
Tetrahedron Asymmetry, 2002 , vol. 13, # 20 p. 2229 - 2234
反应条件
1: 70 percent / DBU / toluene / 24 h / Heating 2: 68 percent / lithium / tetrahydrofuran; ethanol; liquid ammonia / 0.25 h / Heating View Scheme
参考文献
Hendrie, Shirley K.; Leonard, John
Tetrahedron, 1987 , vol. 43, # 14 p. 3289 - 3294
反应条件
1: 78 percent / NaIO4, RuO2 / H2O; ethyl acetate / 0.5 h / 0 °C 2: 1.) trifluoroacetic acid (TFA), 2.) 2 M aq. NaOH / 1.) CHCl3, reflux, 24 h, 2.) 90 deg C, 1 h View Scheme
参考文献
Alker; Doyle; Harwood; McGregor
Tetrahedron Asymmetry, 1990 , vol. 1, # 12 p. 877 - 880
反应条件
sodium hydroxide; trifluoroacetic acid 1.) CHCl3, reflux, 24 h, 2.) 90 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Alker; Doyle; Harwood; McGregor
Tetrahedron Asymmetry, 1990 , vol. 1, # 12 p. 877 - 880
