4-羟基-1-甲基双环[2.2.2]辛烷-2-酮合成路线 (共 5 条)
反应条件
potassium hydroxide; water T=70°C; 6 h; Heating;
参考文献
Gray, George W.; Kelly, Stephen M.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1981 , p. 26 - 31
反应条件
(i) (heating), (ii) aq. KOH; Multistep reaction;
参考文献
Colonge,J.; Vuillemet,R.
Bulletin de la Societe Chimique de France, 1961 , p. 2235 - 2236
反应条件
1: 74 percent / sodium hydroxide, water / 10 h / Heating 2: 63 percent / acetic anhydride / 14 h / Heating 3: 71 percent / potassium hydroxide, water / 6 h / 70 °C / Heating View Scheme
参考文献
Kraus,W. et al.
Tetrahedron, 1969 , vol. 25, p. 3681 - 3692
反应条件
pyridine hydrochloride T=200 - 210°C;
参考文献
Morita,K.-I. et al.
Journal of Organic Chemistry, 1965 , vol. 30, p. 533 - 538
参考文献
Suzuki,Z.; Morita,K.
Journal of Organic Chemistry, 1967 , vol. 32, p. 31 - 34