potassium tert-butylate; copper(l) chloride; 1,3-bis(2,6-diisopropylphenyl)imidazolinium chloride in tetrahydrofuran T=70°C; P=760.051 Torr; 24 h;

1: With sodium hydroxide in methanol T=23°C; 0.25 h; Inert atmosphere; 2: With silver trifluoromethanesulfonate in methanol T=0°C; 0.5 h; Inert atmosphere; 3: With 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate) in hexadeuterioacetone T=23°C; 1 h; Inert atmosphereMolecular sieve; regiospecific reaction;

in benzene

potassium phosphate; Ni(PCy3)2Cl2 in ethylene glycol dimethyl ether; toluene T=120°C; 48 h; Inert atmosphere;

1: (i) Mg, (ii) B(OMe)3, (iii) H2SO4 2: benzene View Scheme