3,4-二甲氧基-2-甲基苯甲醛合成路线 （共 21 条）
反应条件
potassium permanganate in acetone
参考文献
Grethe,G. et al.
Journal of Organic Chemistry, 1968 , vol. 33, # 2 p. 494 - 503
反应条件
1.1: potassium tert-butylate / N,N-dimethyl-formamide / 20 °C 2.1: acetic anhydride; sodium carbonate / acetic acid / Reflux 2.2: Reflux 3.1: potassium carbonate / acetone / 24 h / 20 °C View Scheme
参考文献
Le, Tin Thanh; Chau, Nguyet Trang Thanh; Nguyen, Tai Tan; Brien, Josselin; Thai, Trieu Tien; Nourry, Arnaud; Castanet, Anne-Sophie; Nguyen, Kim Phi Phung; Mortier, Jacques
Journal of Organic Chemistry, 2011 , vol. 76, # 2 p. 601 - 608
反应条件
1.1: potassium tert-butylate / N,N-dimethyl-formamide / 20 °C 2.1: acetic anhydride; sodium carbonate / acetic acid / Reflux 2.2: Reflux 3.1: potassium carbonate / acetone / 24 h / 20 °C 4.1: potassium hydroxide / water / Reflux View Scheme
参考文献
Le, Tin Thanh; Chau, Nguyet Trang Thanh; Nguyen, Tai Tan; Brien, Josselin; Thai, Trieu Tien; Nourry, Arnaud; Castanet, Anne-Sophie; Nguyen, Kim Phi Phung; Mortier, Jacques
Journal of Organic Chemistry, 2011 , vol. 76, # 2 p. 601 - 608
反应条件
1.1: potassium tert-butylate / N,N-dimethyl-formamide / 20 °C 2.1: acetic anhydride; sodium carbonate / acetic acid / Reflux 2.2: Reflux View Scheme
参考文献
Le, Tin Thanh; Chau, Nguyet Trang Thanh; Nguyen, Tai Tan; Brien, Josselin; Thai, Trieu Tien; Nourry, Arnaud; Castanet, Anne-Sophie; Nguyen, Kim Phi Phung; Mortier, Jacques
Journal of Organic Chemistry, 2011 , vol. 76, # 2 p. 601 - 608
反应条件
1.1: potassium tert-butylate / N,N-dimethyl-formamide / 20 °C 2.1: acetic anhydride; sodium carbonate / acetic acid / Reflux 2.2: Reflux 3.1: potassium carbonate / acetone / 24 h / 20 °C 4.1: potassium hydroxide / water / Reflux 5.1: 2,2,6,6-tetramethylpiperidinyl-lithium / tetrahydrofuran / 0 - 20 °C 5.2: 2 h / 20 °C View Scheme
参考文献
Le, Tin Thanh; Chau, Nguyet Trang Thanh; Nguyen, Tai Tan; Brien, Josselin; Thai, Trieu Tien; Nourry, Arnaud; Castanet, Anne-Sophie; Nguyen, Kim Phi Phung; Mortier, Jacques
Journal of Organic Chemistry, 2011 , vol. 76, # 2 p. 601 - 608
反应条件
tin(IV) chloride in dichloromethane
a) 0 deg C, 1 h, b) 0 deg C, 1 h, c) to room temperature;
参考文献
Meier, Herbert; Kretzschmann, Holger; Kolshorn, Heinz
Journal of Organic Chemistry, 1992 , vol. 57, # 25 p. 6847 - 6852
反应条件
pyridinium chlorochromate in dichloromethane
1 h; Ambient temperature;
参考文献
Borchardt, Ronald T.; Bhatia, Pramila
Journal of Medicinal Chemistry, 1982 , vol. 25, # 3 p. 263 - 271
反应条件
n-butyllithium in tetrahydrofuran
参考文献
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
Patent: WO2006/83417 A2, 2006 ;
Location in patent: Example 5 ;
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran
2: With pyridinium chlorochromate
参考文献
Le, Tin Thanh; Chau, Nguyet Trang Thanh; Nguyen, Tai Tan; Brien, Josselin; Thai, Trieu Tien; Nourry, Arnaud; Castanet, Anne-Sophie; Nguyen, Kim Phi Phung; Mortier, Jacques
Journal of Organic Chemistry, 2011 , vol. 76, # 2 p. 601 - 608
反应条件
sodium hydroxide in water
T=100°C;
参考文献
Buszek, Keith R.; Bixby, Dale L.
Tetrahedron Letters, 1995 , vol. 36, # 50 p. 9129 - 9132
