alpha-去甲基苯恶洛芬合成路线 (共 3 条)
参考文献
Lilly Industries, Ltd.
Patent: US4025636 A1, 1977 ;
反应条件
hydrogenchloride in methanol
4 h; Heating;
参考文献
Huegel, Helmut M.
Synthetic Communications, 1985 , vol. 15, # 12 p. 1075 - 1080
反应条件
1: 100 percent / H2, NaHCO3 (aq.) / Pd on charcoal / 4 h / 3102.9 Torr
2: 63.9 percent / HCl / methanol / 4 h / Heating
View Scheme
参考文献
Huegel, Helmut M.
Synthetic Communications, 1985 , vol. 15, # 12 p. 1075 - 1080