2-溴-3-甲基丁烯酸甲酯合成路线 （共 10 条）
反应条件
1: With bromine in tetrachloromethane T=25°C; Bromination; 1 h; 2: With triethylamine in dichloromethane T=0 - 25°C; Elimination;
参考文献
Lloveras, Maia; Ramos, Isabel; Molins, Elies; Messeguer, Angel
Tetrahedron, 2000 , vol. 56, # 21 p. 3391 - 3397
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran T=-78°C; 1.5 h;
参考文献
Mori, Hajime; Ikoma, Keiichi; Isoe, Sachihiko; Kitaura, Kazuo; Katsumura, Shigeo
Journal of Organic Chemistry, 1998 , vol. 63, # 24 p. 8704 - 8718
反应条件
bromine in tetrahydrofuran; water; acetone
参考文献
THE UPJOHN COMPANY
Patent: EP232017 A1, 1987 ;
反应条件
1: thionyl chloride 2: Cl2, Br2 / CCl4 / 48 h / from -50 deg C to -70 deg C 3: triethylamine / 72 h View Scheme
参考文献
Korhonen, Ilpo O. O.; Pitkaenen, Maija; Korvola, Jorma N. J.
Tetrahedron, 1982 , vol. 38, # 18 p. 2837 - 2841
参考文献
Korhonen, Ilpo O. O.; Pitkaenen, Maija; Korvola, Jorma N. J.
Tetrahedron, 1982 , vol. 38, # 18 p. 2837 - 2841
参考文献
Owen; Somade
Journal of the Chemical Society, 1947 , p. 1033
Full Text Show Details
Owen; Sultanbawa
Journal of the Chemical Society, 1949 , p. 3104
反应条件
2: methylalcoholic H2SO4 View Scheme
参考文献
Owen; Sultanbawa
Journal of the Chemical Society, 1949 , p. 3104
反应条件
1: 40 percent / NBS / CCl4 / Irradiation 2: 48 percent / conc. HBr (48 percent) / 8 h / Heating View Scheme
参考文献
Lloveras, Maia; Ramos, Isabel; Molins, Elies; Messeguer, Angel
Tetrahedron, 2000 , vol. 56, # 21 p. 3391 - 3397
反应条件
1: K2CO3 / acetone
2: aq. NaOH / methanol
3: H2 / Pd-C
View Scheme
参考文献
Padmanathan,T.; Sultanbawa,M.U.S.
Journal of the Chemical Society, 1963 , p. 4210 - 4218
反应条件
in tetrahydrofuran; diethyl ether
T=0°C; 8 h;
参考文献
Mori, Hajime; Ikoma, Keiichi; Isoe, Sachihiko; Kitaura, Kazuo; Katsumura, Shigeo
Journal of Organic Chemistry, 1998 , vol. 63, # 24 p. 8704 - 8718
