4-(乙氧基羰基甲氧基)苯甲醛合成路线 （共 23 条）
反应条件
1: 95 percent / piperidine / ethanol / 4 h / Heating 2: 70 percent / hydrazine hydrate / ethanol / 4 h / Heating 3: 75 percent / gl. acetic acid / ethanol / 3 h / Heating View Scheme
参考文献
Mohan, Rajiv Ravindra; Agarwal, Chapla; Misra, V. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 339 - 341
反应条件
1: 95 percent / piperidine / ethanol / 4 h / Heating 2: 70 percent / hydrazine hydrate / ethanol / 4 h / Heating 3: 55 percent / gl. acetic acid / ethanol / 3 h / Heating View Scheme
参考文献
Mohan, Rajiv Ravindra; Agarwal, Chapla; Misra, V. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 339 - 341
反应条件
1: propionic acid 2: KOH / ethanol View Scheme
参考文献
Syrbu, S. A.; Semeikin, A. S.; Berezin, B. D.; Koifman, O. I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1989 , vol. 25, # 10 p. 1149 - 1153
Khimiya Geterotsiklicheskikh Soedinenii, 1989 , vol. 25, # 10 p. 1373 - 1377
反应条件
1: 4-hydroxy-benzaldehyde With potassium carbonate; sodium iodide in acetonitrile
0.5 h; Heating;
2: ethyl bromoacetate in acetonitrile
18 h; Heating;
参考文献
Bhaumik, Jayeeta; Yao, Zhen; Borbas, K. Eszter; Taniguchi, Masahiko; Lindsey, Jonathan S.
Journal of Organic Chemistry, 2006 , vol. 71, # 23 p. 8807 - 8817
反应条件
sulfuric acid
4 h; Reflux;
参考文献
Dainippon Sumitomo Pharma Co. Ltd.; AstraZeneca AB
Patent: US2011/136801 A1, 2011 ;
Location in patent: Page/Page column 67 ;
反应条件
potassium carbonate; potassium iodide in N,N-dimethyl-formamide
1 h; Heating;
参考文献
Syrbu, S. A.; Semeikin, A. S.; Berezin, B. D.; Koifman, O. I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1989 , vol. 25, # 10 p. 1149 - 1153
Khimiya Geterotsiklicheskikh Soedinenii, 1989 , vol. 25, # 10 p. 1373 - 1377
反应条件
CuCl2·2H2O; water in acetonitrile
T=75°C; 1.5 h;
参考文献
Quan, Na; Shi, Xiao-Xin; Nie, Liang-Deng; Dong, Jing; Zhu, Rui-Heng
Synlett, 2011 , # 7 p. 1028 - 1032
反应条件
potassium carbonate in water; acetone
参考文献
Terumo Kabushiki Kaisha
Patent: US5374641 A1, 1994 ;
反应条件
iodine; potassium carbonate in water; toluene
参考文献
Dr. Reddy's Research Foundation
Patent: US6469167 B1, 2002 ;
反应条件
1: NaOH
2: hydrogen chloride
View Scheme
参考文献
Elkan
Chemische Berichte, 1886 , vol. 19, p. 3051
