3-[(4S)-2,2-二甲基-1,3-二氧戊烷-4-基]-丙醇合成路线 （共 21 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0 - 20°C; 3 h;
参考文献
Sharma; Punna, Sreenivas; Krishna, Palakodety Radha; Chorghade, Mukund S.; Ley, Steven V.
Tetrahedron Asymmetry, 2005 , vol. 16, # 6 p. 1125 - 1133
反应条件
(+/-)-camphor-10-sulfonic acid in acetone T=35°C; 3 h;
参考文献
Kuehnert, Sven M; Maier, Martin E
Organic letters, 2002 , vol. 4, # 4 p. 643 - 646
反应条件
lithium aluminium tetrahydride; sodium carbonate in diethyl ether T=-20°C; 3 h;
参考文献
Larcheveque, Marc; Lalande, Julien
Tetrahedron, 1984 , vol. 40, # 6 p. 1061 - 1066
反应条件
1: (S)-(+)-5-oxo-tetrahydrofuran-2-carboxylic acid With dimethylsulfide borane complex in chloroform T=61°C; 2: acetone With toluene-4-sulfonic acid
参考文献
Ikeda, Shuhei; Shibuya, Masatoshi; Iwabuchi, Yoshiharu
Chemical Communications, 2007 , # 5 p. 504 - 506
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide in diethyl ether; tert-butyl alcohol T=-40°C; 48 h;
参考文献
Larcheveque, Marc; Lalande, Julien
Tetrahedron, 1984 , vol. 40, # 6 p. 1061 - 1066
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 1.) RT, overnight, 2.) reflux, 6 h;
参考文献
Rodriguez, Evelyn B.; Scally, Gavin D.; Stick, Robert V.
Australian Journal of Chemistry, 1990 , vol. 43, # 8 p. 1391 - 1405
反应条件
1: 20.0 g / K2CO3 / H2O / 20 h / 20 °C 2: hydrogen / Pd(OH)2/C / methanol / 2 h 3: 15.6 g / LAH / diethyl ether / 1 h / 0 °C View Scheme
参考文献
Sharma; Punna, Sreenivas; Krishna, Palakodety Radha; Chorghade, Mukund S.; Ley, Steven V.
Tetrahedron Asymmetry, 2005 , vol. 16, # 6 p. 1125 - 1133
反应条件
1: With potassium carbonate; ozone in methanol; dichloromethane T=-78°C; 2: With sodium tetrahydroborate in methanol; dichloromethane T=-78 - 20°C;
参考文献
Morin, Matthew D.; Rychnovsky, Scott D.
Organic Letters, 2005 , vol. 7, # 10 p. 2051 - 2053
反应条件
1: hydrogen / Pd(OH)2/C / methanol / 2 h 2: 15.6 g / LAH / diethyl ether / 1 h / 0 °C View Scheme
参考文献
Kang, Eun Joo; Cho, Eun Jin; Ji, Mi Kyung; Lee, Young Eun; Shin, Dong Mok; Choi, Soo Young; Chung, Young Keun; Kim, Jong-Seo; Kim, Hie-Joon; Lee, Sueg-Geun; Lah, Myoung Soo; Lee, Eun
Journal of Organic Chemistry, 2005 , vol. 70, # 16 p. 6321 - 6329
反应条件
1: NaIO4; NaHCO3 / H2O / 1 h / 20 °C 2: 20.0 g / K2CO3 / H2O / 20 h / 20 °C 3: hydrogen / Pd(OH)2/C / methanol / 2 h 4: 15.6 g / LAH / diethyl ether / 1 h / 0 °C View Scheme
参考文献
Kang, Eun Joo; Cho, Eun Jin; Ji, Mi Kyung; Lee, Young Eun; Shin, Dong Mok; Choi, Soo Young; Chung, Young Keun; Kim, Jong-Seo; Kim, Hie-Joon; Lee, Sueg-Geun; Lah, Myoung Soo; Lee, Eun
Journal of Organic Chemistry, 2005 , vol. 70, # 16 p. 6321 - 6329
