3-[(4S)-2,2-二甲基-1,3-二氧戊烷-4-基]-丙醇合成路线 （共 21 条）
反应条件
1: 99 percent / H2 / PtO2 / ethyl acetate / 4 h / 20 °C / 2068.59 Torr 2: 95 percent / LiAlH4 / tetrahydrofuran / 3 h / 0 - 20 °C View Scheme
参考文献
Sharma; Punna, Sreenivas; Krishna, Palakodety Radha; Chorghade, Mukund S.; Ley, Steven V.
Tetrahedron Asymmetry, 2005 , vol. 16, # 6 p. 1125 - 1133
反应条件
1.1: 56 percent / NaNO2; aq. HCl / 0 °C 2.1: BH3*SMe2 / CHCl3 / 61 °C 2.2: p-TsOH View Scheme
参考文献
Grubb, Lana M.; Branchaud, Bruce P.
Journal of Organic Chemistry, 1997 , vol. 62, # 2 p. 242 - 243
反应条件
1: 70 percent / LiAlH4 / tetrahydrofuran / 20 h / Heating 2: 91 percent / (+/-)-camphersulfonic acid / acetone / 3 h / 35 °C View Scheme
参考文献
Kuehnert, Sven M; Maier, Martin E
Organic letters, 2002 , vol. 4, # 4 p. 643 - 646
反应条件
1: dimethylsulfoxide / 2 h / 90 °C 2: aq. NaOH / ethanol / 3 h / Heating 3: LiAlH4 / tetrahydrofuran / 1 h / Heating View Scheme
参考文献
Koert
Tetrahedron Letters, 1994 , vol. 35, # 16 p. 2517 - 2520
反应条件
lithium aluminium tetrahydride Yield given;
参考文献
Berninger, Joern; Koert, Ulrich; Eisenberg-Hoehl, Christina; Knochel, Paul
Chemische Berichte, 1995 , vol. 128, # 10 p. 1021 - 1028
反应条件
1: aq. NaOH / ethanol / 3 h / Heating 2: LiAlH4 / tetrahydrofuran / 1 h / Heating View Scheme
参考文献
Koert
Tetrahedron Letters, 1994 , vol. 35, # 16 p. 2517 - 2520
反应条件
toluene-4-sulfonic acid Yield given;
参考文献
Gage, Jennifer L.; Branchaud, Bruce P.
Tetrahedron Letters, 1997 , vol. 38, # 40 p. 7007 - 7010
反应条件
toluene-4-sulfonic acid T=20°C; 72 h; Title compound not separated from byproducts;
参考文献
Brimble, Margaret A.; Park, Jae H.; Taylor, Carol M.
Tetrahedron, 2003 , vol. 59, # 31 p. 5861 - 5868
反应条件
1: p-toluenesulphonic acid / 4 h / Heating 2: LiAlH4 / diethyl ether / 1 h / Heating View Scheme
参考文献
Leggeri; Azzolina; Pirillo; Traverso
Farmaco, 1989 , vol. 44, # 3 p. 303 - 313
反应条件
carbon tetrabromide; triphenylphosphine in dichloromethane 0.333333 h; Ambient temperature1.) 0 deg C; Yield given;
参考文献
Leggeri; Azzolina; Pirillo; Traverso
Farmaco, 1989 , vol. 44, # 3 p. 303 - 313
