4-氰基-4-苯基哌嗪合成路线

参考文献

Kuduk, Scott D.; Chang, Ronald K.; Di Marco, Christina N.; Pitts, Daniel R.; Greshock, Thomas J.; Ma, Lei; Wittmann, Marion; Seager, Matthew A.; Koeplinger, Kenneth A.; Thompson, Charles D.; Hartman, George D.; Bilodeau, Mark T.; Ray, William J.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4773 - 4780

140-29-4氰化苄

51304-58-64-氰基-4-苯基哌嗪

参考文献

Kuduk, Scott D.; Chang, Ronald K.; Di Marco, Christina N.; Pitts, Daniel R.; Greshock, Thomas J.; Ma, Lei; Wittmann, Marion; Seager, Matthew A.; Koeplinger, Kenneth A.; Thompson, Charles D.; Hartman, George D.; Bilodeau, Mark T.; Ray, William J.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4773 - 4780

51304-58-64-氰基-4-苯基哌嗪

3627-45-04-苯基-4-哌啶甲酸

参考文献

Abbott Laboratories
Patent: US2004/116518 A1, 2004 ;
Location in patent: Page 91 ;

100-39-0溴化苄+

51304-58-64-氰基-4-苯基哌嗪

56243-25-51-苄基-4-氰基-4-苯基哌啶盐酸盐

参考文献

Aventis Pharmaceuticals Inc.
Patent: EP946548 B1, 2002 ;
EP 0946548 B1

100-39-0溴化苄+

51304-58-64-氰基-4-苯基哌嗪

56243-25-51-苄基-4-氰基-4-苯基哌啶盐酸盐

参考文献

Hoechst Marion Roussel Inc.
Patent: US5824690 A1, 1998 ;
US 5824690 A

51304-58-64-氰基-4-苯基哌嗪

24465-45-04-苯基-4-乙氧甲酰哌啶盐酸盐

参考文献

Pfizer Inc
Patent: US5936089 A1, 1999 ;

51304-58-64-氰基-4-苯基哌嗪

771-99-34-苯基哌啶

参考文献

Berkoff, Charles E.; Rivard, Donald E.; Kirkpatrick, David; Ives, Jeffrey L.
Synthetic Communications, 1980 , vol. 10, # 12 p. 939 - 946

24424-99-5二碳酸二叔丁酯+

51304-58-64-氰基-4-苯基哌嗪

158144-79-74-氰基-4-苯基哌啶-1-羧酸叔丁酯

参考文献

Duan, Maosheng; Aquino, Christopher; Ferris, Robert; Kazmierski, Wieslaw M.; Kenakin, Terry; Koble, Cecilia; Wheelan, Pat; Watson, Chris; Youngman, Michael
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 6 p. 1610 - 1613

34619-03-9+

51304-58-64-氰基-4-苯基哌嗪

158144-79-74-氰基-4-苯基哌啶-1-羧酸叔丁酯

参考文献

SMITHKLINE BEECHAM CORPORATION
Patent: WO2004/54974 A2, 2004 ;
Location in patent: Page 48 ;
WO 2004/054974 A2

24424-99-5二碳酸二叔丁酯+

51304-58-64-氰基-4-苯基哌嗪

158144-82-2

参考文献

Dinnell, Kevin; Elliott, Jason Matthew; Hollingworth, Gregory John; Ridgill, Mark Peter; Shaw, Duncan Edward
Patent: US2001/39286 A1, 2001 ;