2-溴-2-羟基-5-甲基苯乙酮合成路线 （共 5 条）
反应条件
copper(ll) bromide in chloroform; ethyl acetate
T=100°C; 18 h;
参考文献
SMITHKLINE BEECHAM CORPORATION; BOUILLOT, Anne Marie Jeanne; DODIC, Nerina; GELLIBERT, Francoise Jeanne; MIRGUET, Olivier
Patent: WO2010/15652 A2, 2010 ;
Location in patent: Page/Page column 31 ;
WO 2010/015652 A2
反应条件
aluminium trichloride
T=125°C;
参考文献
Wittig
Justus Liebigs Annalen der Chemie, 1926 , vol. 446, p. 179
参考文献
Oelschlager; Moussa
Archiv der Pharmazie, 1973 , vol. 306, # 11 p. 807 - 812
反应条件
1: 150 °C
2: aluminium chloride / 125 °C
View Scheme
参考文献
Wittig
Justus Liebigs Annalen der Chemie, 1926 , vol. 446, p. 179
反应条件
sodium acetate in N,N-dimethyl-formamide
1 h; Heating;
参考文献
Deshpande, A.R.; Paradkar, M.V.
Synthetic Communications, 1990 , vol. 20, # 6 p. 809 - 816
