2,2-二甲基-[1,3]二恶烷-5,5-二甲酸二乙酯合成路线 (共 11 条)
反应条件
1: 74 percent / aq. NaCl / dimethylsulfoxide / 24 h / 180 °C
2: LiAlH4 / diethyl ether / 5 h / Ambient temperature
3: pyridine / 3 h / Ambient temperature
4: NaI / acetone / 12 h / 50 °C
View Scheme
参考文献
Schiller, Radan; Tichotova, Lucie; Pavlik, Jan; Buchta, Vladimir; Melichar, Bohuslav; Votruba, Ivan; Kunes, Jiri; Spulak, Marcel; Pour, Milan
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 24 p. 7358 - 7360