N-[2-(4-硝基苯氧基)乙基]-N,N-二甲基胺合成路线 （共 13 条）
反应条件
hydrogen; palladium 10 on activated carbon in tetrahydrofuran; methanol P=5250.53 Torr; 16 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: WO2008/77885 A2, 2008 ;
Location in patent: Page/Page column 22 ;
WO 2008/077885 A2
反应条件
1: 82 percent / 0.5 h / 0 °C
2: 1.) 50percent sulfuric acid, sodium nitrite; 2.) urea, sodium iodide-127, sodium sulfite / 1.) 0 deg C, 10 min, water; 2.) 10 min, 0 deg C, water; 3.) 10 min, r.t.; 4.) 6 min, 80 deg C
View Scheme
参考文献
Hunter; Zea Ponce; Brown; et al.
Canadian Journal of Chemistry, 1984 , vol. 62, # 10 p. 2015 - 2018
反应条件
1: 82 percent / 0.5 h / 0 °C
2: 1.) 50percent sulfuric acid, sodium nitrite; 2.) urea, sodium iodide-127, sodium sulfite / 1.) 0 deg C, 10 min, water; 2.) 10 min, 0 deg C, water; 3.) 10 min, r.t.; 4.) 6 min, 80 deg C
3: 95 percent / CHCl3 / 0.5 h / Ambient temperature
View Scheme
参考文献
Hunter; Zea Ponce; Brown; et al.
Canadian Journal of Chemistry, 1984 , vol. 62, # 10 p. 2015 - 2018
