2,6-二甲基-2,3-二氢-4H-苯并吡喃-4-酮合成路线 （共 13 条）
反应条件
oxygen; potassium carbonate; palladium diacetate in ethanol; water
T=35°C; Wacker-type oxidative cyclization; P=760.051 Torr; 24 h;
参考文献
Zhang, Zuhui; Pan, Chongfeng; Wang, Zhiyong
Chemical Communications, 2007 , # 44 p. 4686 - 4688
反应条件
1: With sodium hydroxide in water
T=20°C; 16 h;
2: With methanol; sodium methylate
T=20°C; 5 h;
参考文献
Hori, Kenji; Sadatomi, Hirotaka; Miyamoto, Atsuo; Kuroda, Takaaki; Sumimoto, Michinori; Yamamoto, Hidetoshi
Molecules, 2010 , vol. 15, # 11 p. 8289 - 8304
反应条件
ethylene glycol
T=180°C; 0.666667 h;
参考文献
Ariamala, G.; Balasubramanian, K. K.
Tetrahedron, 1989 , vol. 45, # 1 p. 309 - 318
反应条件
in ethylene glycol
T=180°C; 0.666667 h; Heating;
参考文献
Ariamala, G.; Balasubramanian, K.K.
Tetrahedron Letters, 1988 , vol. 29, # 28 p. 3487 - 3488
反应条件
ethylene glycol
T=180°C;
参考文献
Ariamala, G.; Balasubramanian, K. K.
Tetrahedron, 1989 , vol. 45, # 1 p. 309 - 318
参考文献
Dann et al.
Justus Liebigs Annalen der Chemie, 1954 , vol. 587, p. 16,36
反应条件
1: Br2, aq. NaOH / 1,2-dimethoxy-ethane
2: 65 percent / ethylene glycol / 180 °C
View Scheme
参考文献
Ariamala, G.; Balasubramanian, K. K.
Tetrahedron, 1989 , vol. 45, # 1 p. 309 - 318
反应条件
sodium hydroxide
5 h; Ambient temperature; Yield given;
参考文献
Miranda, Miguel A.; Primo, Jaime; Tormos, Rosa
Tetrahedron, 1987 , vol. 43, # 10 p. 2323 - 2328
反应条件
PPA; Polyphosphoric acid (PPA)
1.) 120 degC, 3 h, 2.) 140 deg C, 5 h; Multistep reaction;
参考文献
Lipinski, Christopher A.; Aldinger, Charles E.; Beyer, Thomas A.; Bordner, Jon; Burdi, Douglas F.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 12 p. 2169 - 2177
反应条件
sodium hydroxide
5 h; Ambient temperature; Yield given;
参考文献
Miranda, Miguel A.; Primo, Jaime; Tormos, Rosa
Tetrahedron, 1987 , vol. 43, # 10 p. 2323 - 2328
