5-(2-甲基苯基)-1H-四唑合成路线 （共 6 条）
反应条件
diethylaluminium azide in xylene T=80°C; 25 h;
参考文献
Aureggi, Valentina; Sedelmeier, Gottfried
Angewandte Chemie - International Edition, 2007 , vol. 46, # 44 p. 8440 - 8444
反应条件
1: (tetrazol-5-yl)benzene With N,N,N',N,-tetramethylethylenediamine; sec.-butyllithium in tetrahydrofuran T=-30°C; 1 h; 2: methyl iodide in tetrahydrofuran T=-30 - 20°C;
参考文献
Rhonnstad, Patrik; Wensbo, David
Tetrahedron Letters, 2002 , vol. 43, # 17 p. 3137 - 3139
参考文献
Flippin, Lee A.
Tetrahedron Letters, 1991 , vol. 32, # 47 p. 6857 - 6860
反应条件
in dimethylsulfoxide-d6; chloroform-d1 Equilibrium constant;
参考文献
Butler, Richard N.; Garvin, Victor C.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 390 - 393
反应条件
in dimethylsulfoxide-d6; chloroform-d1 Equilibrium constant;
参考文献
Butler, Richard N.; Garvin, Victor C.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 390 - 393
反应条件
N,N,N',N,-tetramethylethylenediamine; sec.-butyllithium 1) THF, cyclohexane, -35 to 30 deg C, 2) to room temperature; Yield given. Multistep reaction;
参考文献
Flippin, Lee A.
Tetrahedron Letters, 1991 , vol. 32, # 47 p. 6857 - 6860
