[双(甲硫基)亚甲基]丙烷二腈合成路线

参考文献

MILLENNIUM PHARMACEUTICALS, INC.; TAKEDA PHARMACEUTICAL COMPANY LIMITED; BANNO, Hiroshi; HIROSE, Masaaki; KURASAWA, Osamu; LANGSTON, Steven, P.; MIZUTANI, Hirotake; SHI, Zhan; VISIERS, Irache; VOS, Tricia, J.; VYSKOCIL, Stepan
Patent: WO2010/90716 A1, 2010 ;
Location in patent: Page/Page column 217-218 ;

5147-80-8[双(甲硫基)亚甲基]丙烷二腈

116170-90-23-氨基-4-氰基-5-(甲基硫代)-噻吩-2-羧酸乙酯

参考文献

Aventis Pharma S.A.
Patent: US2008/146542 A1, 2008 ;
Location in patent: Page/Page column 18 ;

5147-80-8[双(甲硫基)亚甲基]丙烷二腈+

2365-48-2巯基乙酸甲酯

129332-45-23-氨基-4-氰基-5-甲硫基噻吩-2-甲酸甲酯

参考文献

MILLENNIUM PHARMACEUTICALS, INC.
Patent: WO2009/94224 A1, 2009 ;
Location in patent: Page/Page column 49-50 ;

5147-80-8[双(甲硫基)亚甲基]丙烷二腈+

74497-02-2

17823-65-3

参考文献

Mukaiyama, Harunobu; Nishimura, Toshihiro; Shiohara, Hiroaki; Kobayashi, Satoko; Komatsu, Yoshimitsu; Kikuchi, Shinji; Tsuji, Eiichi; Kamada, Noboru; Ohnota, Hideki; Kusama, Hiroshi
Chemical and Pharmaceutical Bulletin, 2007 , vol. 55, # 6 p. 881 - 889

124-42-5盐酸乙脒+

5147-80-8[双(甲硫基)亚甲基]丙烷二腈

135158-59-74-氨基-5-氰基-2-甲基-6-甲基硫代嘧啶

参考文献

Ram, Vishnu J; Haque, Navedul; Nath, Mahendra
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 7 p. 754 - 759

5147-80-8[双(甲硫基)亚甲基]丙烷二腈+

100-46-9苄胺

152588-23-3

参考文献

Hirosa, Miki; Hagimori, Masayori; Shigemitsu, Yasuhiro; Mizuyama, Naoko; Wang, Bo-Cheng; Tominaga, Yoshinori
Heterocycles, 2009 , vol. 78, # 4 p. 899 - 903

60-35-5乙酰胺+

5147-80-8[双(甲硫基)亚甲基]丙烷二腈

15908-63-15-氰基-2-甲基-6-(甲基硫代)嘧啶-4(3H)-酮

参考文献

Kohra, Shinya; Tominaga, Yoshinori; Hosomi, Akira
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 959 - 968

5147-80-8[双(甲硫基)亚甲基]丙烷二腈

175202-48-94-氰基-5-(甲硫基)噻吩-2-羟酸甲酯

参考文献

Weinstock, Joseph; Wu, Jian; Cao, Ping; Kingsbury, William D.; McDermott, Jeffrey L.; Kodrasov, Matthew P.; McKelvey, Devin M.; Suresh Kumar, K. G.; Goldenberg, Seth J.; Mattern, Michael R.; Nicholson, Benjamin
Medicinal Chemistry letters, 2012 , vol. 3, # 10 p. 789 - 792,4
Title/Abstract Full Text Show Details
Weinstock, Joseph; Wu, Jian; Cao, Ping; Kingsbury, William D.; McDermott, Jeffrey L.; Kodrasov, Matthew P.; McKelvey, Devin M.; Suresh Kumar; Goldenberg, Seth J.; Mattern, Michael R.; Nicholson, Benjamin
ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 10 p. 789 - 792

5147-80-8[双(甲硫基)亚甲基]丙烷二腈

118996-61-54-氯-6-甲基磺酰基-2-苯基-5-嘧啶甲腈

参考文献

Journal of Heterocyclic Chemistry, , vol. 25, p. 959 - 968

5147-80-8[双(甲硫基)亚甲基]丙烷二腈+

2051-95-83-苯丙烯溴酸酯

114361-51-2

参考文献

Tominaga, Yoshinori; Kawabe, Masanori; Hosomi, Akira
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 1325 - 1331