1: AcOH / methanol / 24 h / 20 °C 2: POCl3 / pyridine / 0.25 h / Heating 3: 79.9 percent / H2SO4 / acetic acid / 3 h 4: 70.3 percent / H2 / Pd/C / ethanol / 8 h / 50 °C / 75.01 Torr 5: 70.5 percent / dichlorodicyanobenzoquinone; bis(trimethylsilyl)trifluoro acetamide / dioxane / 18 h / Heating View Scheme

1: AcOH / methanol / 24 h / 20 °C 2: POCl3 / pyridine / 0.25 h / Heating 3: 79.9 percent / H2SO4 / acetic acid / 3 h 4: 70.3 percent / H2 / Pd/C / ethanol / 8 h / 50 °C / 75.01 Torr View Scheme